• Home
  • Wellness Articles
  • Contact

Wellcast

Womens Health, Wellness and Integrative Health.

Home » How Celiac Disease Causes Liver Damage

How Celiac Disease Causes Liver Damage

August 23, 2007 By Deborah

Facebook1
Twitter17
Google+0
Pinterest0
LinkedIn0

women, whole health, wellness

I often recommend lab work for my patients to make sure there are no hidden medical problems that need attention. Sometimes I come across elevated liver enzymes. After ruling out hepatitis, and getting an ultrasound; I will check for gluten allergy.

So what is the relationship between having a gluten allergy and the liver?
Well, there are toll-like receptors (TLR) on the surface of many cells which participate in the immune system. These receptors sense molecules that are present in pathogens but not the host. When the immune system senses these molecules, chemicals are released which set off inflammatory and anti-pathogen responses. One class of molecules recognized by TLRs and common to most pathogenic bacteria is something called lipopolysaccharides (LPS).
Gluten increases the permeability of the intestine in those with celiac disease. The disruption of the intestinal barrier allows endotoxins, such as LPS, from gut bacteria to reach the portal vein of the liver triggering a TLR response from immune cells in the liver. Inflammatory mediators are released that triggers more chemicals to flow in tissues that leads to inflammation and liver damage. Gluten itself could also trigger a liver immune response where the Kupffer cells in the liver initiate a T-cell response to gluten within the liver.

Pretty interesting stuff!
You can find out more by logging into www.celiac.com.

Technorati Tags:
wellness, health, food, nutrition, women’s health, womens health

Related

Filed Under: Allergies, Health, Wellness, WomensHealth

Looking for Something?

A Little About Me

Debbie is a board certified family nurse practitioner with an emphasis on women's health. During the past 22 years she has worked in women's health and family practice with a focus on the integration of conventional and alternative therapies.

Email Updates

Sign up to receive email updates for the latest in health and wellness.

Connect with us online

  • Twitter

Latest Tweets

  • The Disproportionate Gender Differences of COVID 19 is.gd/gxdLV8

    About 4 hours ago

  • Natural Acne Treatments wellcast.org/natural-acne-trea…

    About 13 hours ago

  • Marijuana and Pregnancy- Not Recommended is.gd/0WlSEl

    Yesterday at 7:16 pm

  • 4 New Advanced Heart Disease Tools is.gd/GkXVjn

    February 1, 2023 10:16 am

  • COVID-19 Is Not Over Yet is.gd/GnSCSj

    February 1, 2023 1:16 am

Copyright © 2023 · Genesis Framework · WordPress · Log in